Table 3. Levels of GH, IGF-1, DHEA-S and testosterone (ng/ml) in serum of intact Wistar and OXYS rats at the age of 3, 19 and 23 months and of rats treated with SkQ1 or NAC from the age of 19 months to 23 months.

Strain	Age, month	Treatment	GH	IGF-1	Testosterone	DHEA
Wistar	3	0	8.14±0.2	535±62	1.42±0.3	-
	19	0	5.28±0.1+	483±7	0.61±0.04+	0.66±0.01
	23	0	4.98±0.2+	448±12+	0.60±0.07	0.63±0.02+
		SkQ1	5.50±0.1 #^	500 ± 9#	0.61±0.05	0.66±0.01
		NAC	5.37±0.2^	486±10#	0.61±0.03	0.66±0.03
OXYS	3	0	6.24±0.3*	498±64	1.99±0.31	-
	19	0	4.57±0.1 *+	444±7*+	0.64±0.06+	0.58±0.01*
	23	0	4.27±0.1*+	399±9*+	0.56±0.02	0.55±0.03*+
		SkQ1	4.80±0.1#^	499±9 #^	0.58±0.02	0.60±0.02^
		NAC	4.58±0.08^	449±13#	0.57±0.02	0.59±0.02

^*statistically-significant difference between the strains of the same age;

^#significant effect of the drug within the strain;

⁺significant age-related differences from the previous age within the strain,

^{^}statistically-significant difference between the levels before and after treatment with SkQ1 or NAC (paired-dependent comparisons of the same animals).