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. Author manuscript; available in PMC: 2013 Mar 20.
Published in final edited form as: Neuron. 2012 Sep 20;75(6):1067–1080. doi: 10.1016/j.neuron.2012.07.009

Fig. 5. Normalized complexity map for nElavl-dependent alternative splicing.

Fig. 5

(A) nElavl tags mapping to nElavl-regulated cassette exons or flanking introns are plotted onto a composite transcript as a function of distance to the 5’ or 3’ junctions of the alternative exon. Tags from independent CLIP experiments are color-coded. Red and grey boxes represent a generic alternative cassette exon and flanking constitutive exons, respectively. (B) Normalized complexity map of nElavl-dependent alternative splicing of cassette exons. Red and blue peaks represent binding associated with nElavl-dependent exon inclusion and exclusion, respectively. Motif preferences of 250 nt sequences flanking nElavl-regulated alternative exons are shown. (C) Motif preferences of 250 nt sequences flanking randomly selected alternative exons that display no change in isoform abundance in DKO mice are shown. See also Fig.S2 and Table S8.