Fig. 4.

Phylogentic tree of the predicted P. pacificus kinome. The tree shows the phylogentic relationships of predicted kinase domains and their classification into kinase groups according to the C. elegans kinome. Phylogenetic distances are based on multiple sequence alignments of predicted kinase domains. The classification of domains into kinase groups is shown by the different colors of the branches. Red rectangles at the outer edge of the circle indicate kinases that are detected as phosphorylated; green rectangles indicate kinases that are detected as nonphosphorylated in our study.