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. 2012 Sep 22;11(12):1898–1912. doi: 10.1074/mcp.M112.019661

Table II. Effective dose 50% (ED50) of ATO, ODPC, or perifosine for the inhibition of the proliferation of NB4 wild type (NB4 WT) and LAT2 knockdown NB4 (NB4 LAT2KD) cells.

NB4 WT
NB4 LAT2KD
Relative drug susceptibilitya
ED50m) 95% CIb r ED50m) 95% CIb r NB4 WT/NB4 LAT2KD
ATO 8.76 5.36 to 14.34 0.94 1.03 0.92 to 1.15 0.98 8.50
ODPC 23.49 19.79 to 27.88 0.95 3.12 1.83 to 5.28 0.92 7.53
Perifosine 18.67 16.48 to 21.17 0.97 6.10 4.45 to 8.37 0.91 3.06

a Ratio calculated by averaging ED50.

b 95% CI is the 95% confidence interval for ED50, expressed in μm.