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. 2012 Oct 16;9:38. doi: 10.1186/1743-8977-9-38

Table 6.

Serum Cytokine Profile 1 Day post Oropharyngeal Aspiration of 100 μg MWCNTs (pg/ml)

Cytokine/Treatment SS C-grade COOH N-doped
Eotaxin
306.4 ± 75.0
276.9 ± 42.3
903.8 ± 278.6*
302.6 ± 22
IL-5
16.3 ± 1.1
30.3 ± 10.0
11.6 ± 3.0
51.2 ± 28.3
IL-6
9.2 ± 1.3
16.1 ± 7.8
137.8 ± 66.0
42.4 ± 26.4
IL-10
8.5 ± 1.9
8.6 ± 3.4
24.6 ± 15.4
125.8 ± 118.1
IL-12 (p40)
17.5 ± 3.6
20.3 ± 5.3
16.3 ± 2.2
12.6 ± 2.2
IL-12 (p70)
35 ± 5.9
55.3 ± 34.9
22.9 ± 3.1
516.7 ± 464.5
IL-13
446.3 ± 41.6
326.9 ± 38.2
365.3 ± 45.6
848.3 ± 490.0
KC
173.2 ± 32.6
97.1 ± 7.1
645.1 ± 441.3
183.5 ± 53.1
MCP-1
39.6 ± 12.3
36.6 ± 8.6
46.6 ± 6.0
136.1 ± 104.4
MIP1α
38.2 ± 9.3
71.1 ± 4.5
42.0 ± 4.4
128.1 ± 86.9
MIP-1β
129.0 ± 11.4
70.2 ± 22.3
82.8 ± 29.6
136.2 ± 48.8
MIP-2
155.4 ± 27.7
86.4 ± 43.8
209.1 ± 38.9
102.4 ± 26.4
RANTES
30.7 ± 5.8
36.1 ± 6.4
57.5 ± 12.0
65.9 ± 38.5
†IL-1β
33.25 ± 3.83
222.86 ±114.71
127.66 ± 45.32
47.25 ± 7.36
†TNF-α N.D. N.D. N.D. N.D.

Serum cytokine profile by Lincoplex Cytokine/Chemokine 20 plex kit 1 day post oropharyngeal aspiration of three forms of MWCNTs at 100 μg and vehicle control SS (10% surfactant saline). Data reported as mean ± SEM for n = 4. * indicates significance from SS, P ≤ 0.05.

† IL-1β and TNF-α profile 1 day post oropharyngeal aspiration of three forms of MWCNTs at 100 μg and vehicle control SS (10% surfactant saline) by ELISA. Data reported as mean ± SEM for n = 6. N.D. not detected, P ≤ 0.05 by one way- ANOVA.

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