Table 1.
Changes in systolic blood pressure and diastolic blood pressure
|
Systolic blood pressure changes (mmHg) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| |
High-response group |
Low-response group |
||||||||||
| |
Mean blood pressure |
SEM |
Mean blood pressure |
SEM |
||||||||
| Caffeine | L-theanine | Placebo | Caffeine | L-theanine | Placebo | Caffeine | L-theanine | Placebo | Caffeine | L-theanine | Placebo | |
| Base |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
| AMT1 |
4.83 |
7.17 |
12.17 |
5.75 |
4.85 |
3.58 |
10.32 |
5.78 |
6.82 |
3.02 |
7.25 |
3.12 |
| AMT2 |
3.05 |
5.55 |
13.82 |
3.48 |
6.04 |
3.48 |
5.62 |
2.07 |
1.36 |
3.84 |
5.23 |
2.06 |
| AMT3 |
5.10 |
−0.36 |
17.68 |
2.95 |
8.50 |
3.24 |
5.78 |
4.31 |
3.98 |
2.89 |
5.80 |
2.01 |
| AMT4 |
7.95 |
−0.49 |
21.35 |
3.24 |
5.45 |
3.36 |
5.98 |
9.05 |
3.64 |
5.19 |
4.79 |
2.39 |
| AMT5 |
8.08 |
2.88 |
21.82 |
3.71 |
2.66 |
5.46 |
6.92 |
9.28 |
2.75 |
4.25 |
5.35 |
2.56 |
| AMT6 |
10.75 |
5.01 |
22.41 |
3.55 |
2.21 |
4.47 |
5.91 |
9.98 |
3.28 |
4.47 |
5.75 |
2.63 |
| CPT1 |
5.63 |
4.14 |
15.34 |
5.61 |
3.78 |
7.61 |
−2.63 |
7.00 |
3.19 |
5.17 |
7.55 |
4.03 |
| CPT2 |
3.98 |
10.10 |
12.74 |
7.04 |
7.37 |
10.28 |
−9.26 |
−2.76 |
3.42 |
5.66 |
6.86 |
5.74 |
| CPT3 |
18.58 |
28.22 |
19.57 |
7.20 |
5.92 |
8.47 |
3.98 |
12.31 |
15.95 |
5.00 |
7.35 |
4.41 |
| CPT4 |
29.62 |
36.24 |
28.04 |
8.36 |
8.02 |
7.11 |
16.20 |
23.71 |
25.82 |
4.58 |
5.79 |
3.57 |
| CPT5 |
40.52 |
47.64 |
40.05 |
8.71 |
6.67 |
4.70 |
31.65 |
32.08 |
33.61 |
5.23 |
7.46 |
4.99 |
| CPT6 |
45.36 |
54.15 |
49.15 |
7.15 |
6.22 |
4.24 |
38.10 |
39.48 |
39.24 |
6.85 |
7.55 |
5.25 |
| RP1 |
44.70 |
50.71 |
49.64 |
6.61 |
5.76 |
5.98 |
35.92 |
40.74 |
35.55 |
4.57 |
7.75 |
6.34 |
| RP2 |
43.03 |
43.70 |
46.51 |
7.48 |
6.69 |
6.26 |
35.18 |
43.70 |
36.82 |
5.86 |
7.85 |
6.26 |
| RP3 |
35.78 |
38.82 |
41.28 |
6.13 |
6.70 |
6.77 |
31.30 |
33.81 |
33.41 |
4.95 |
6.94 |
6.57 |
| RP4 |
30.66 |
29.77 |
32.61 |
6.63 |
6.02 |
4.00 |
26.18 |
26.68 |
26.41 |
4.76 |
6.68 |
4.66 |
| RP5 |
25.05 |
24.68 |
24.78 |
6.41 |
5.04 |
2.77 |
24.11 |
20.12 |
21.92 |
4.78 |
5.82 |
4.89 |
| RP6 |
22.99 |
20.92 |
20.12 |
5.56 |
4.09 |
2.23 |
20.73 |
18.22 |
17.99 |
4.70 |
5.20 |
4.58 |
| RP7 |
21.68 |
19.58 |
19.90 |
5.15 |
3.96 |
3.03 |
16.51 |
21.51 |
18.14 |
3.77 |
5.38 |
4.31 |
| RP8 |
19.99 |
16.77 |
21.42 |
5.33 |
3.83 |
2.28 |
15.97 |
19.44 |
17.05 |
4.62 |
5.35 |
2.91 |
| RP9 |
18.95 |
14.82 |
23.78 |
4.52 |
3.25 |
2.61 |
15.17 |
17.75 |
18.78 |
4.82 |
5.95 |
3.62 |
| RP10 |
15.32 |
15.12 |
20.72 |
3.46 |
3.71 |
3.11 |
13.72 |
18.22 |
20.75 |
5.11 |
6.80 |
3.90 |
| RP11 |
15.72 |
16.94 |
17.67 |
3.20 |
5.49 |
3.23 |
15.27 |
18.48 |
22.31 |
4.22 |
6.66 |
4.34 |
| RP12 |
17.25 |
17.55 |
19.34 |
3.29 |
3.98 |
3.38 |
17.28 |
18.84 |
21.79 |
4.70 |
6.35 |
4.66 |
| RP13 |
17.35 |
15.34 |
23.24 |
3.92 |
3.46 |
3.27 |
15.42 |
22.60 |
17.48 |
4.96 |
6.25 |
4.65 |
| RP14 |
15.36 |
16.77 |
20.18 |
3.67 |
5.27 |
3.30 |
14.40 |
18.04 |
15.75 |
5.45 |
5.50 |
3.33 |
| RP15 |
15.06 |
18.07 |
22.38 |
3.85 |
3.84 |
2.66 |
9.80 |
20.72 |
15.35 |
5.23 |
6.03 |
3.03 |
| RP16 |
16.48 |
16.54 |
18.65 |
2.71 |
3.50 |
3.63 |
12.42 |
23.12 |
17.28 |
4.57 |
7.01 |
3.83 |
| RP17 |
18.10 |
17.70 |
17.67 |
3.75 |
2.96 |
3.49 |
13.92 |
19.35 |
18.24 |
4.87 |
5.63 |
3.76 |
| RP18 |
18.33 |
16.40 |
15.70 |
3.04 |
1.96 |
4.23 |
14.43 |
16.14 |
19.36 |
3.91 |
6.94 |
3.10 |
|
Diastolic blood pressure changes (mmHg) | ||||||||||||
| |
High-response group |
Low-response group |
||||||||||
| |
Mean blood pressure |
SEM |
Mean blood pressure |
SEM |
||||||||
| |
Caffeine |
L-theanine |
Placebo |
Caffeine |
L-theanine |
Placebo |
Caffeine |
L-theanine |
Placebo |
Caffeine |
L-theanine |
Placebo |
| Base |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
| AMT1 |
4.96 |
6.00 |
11.74 |
3.66 |
2.30 |
1.97 |
7.41 |
5.87 |
7.14 |
2.65 |
3.20 |
1.62 |
| AMT2 |
4.47 |
5.34 |
12.30 |
2.53 |
1.31 |
3.56 |
2.38 |
1.46 |
4.14 |
2.61 |
2.98 |
2.08 |
| AMT3 |
5.09 |
0.61 |
12.60 |
1.98 |
3.27 |
2.91 |
3.51 |
3.00 |
4.39 |
2.71 |
3.27 |
2.27 |
| AMT4 |
5.73 |
2.14 |
17.07 |
2.39 |
2.20 |
2.83 |
4.22 |
5.31 |
5.39 |
3.34 |
3.22 |
2.00 |
| AMT5 |
5.81 |
5.67 |
16.10 |
2.27 |
3.43 |
4.83 |
5.39 |
4.99 |
4.51 |
2.92 |
3.03 |
1.88 |
| AMT6 |
7.19 |
6.64 |
16.90 |
2.37 |
3.08 |
3.73 |
3.95 |
6.66 |
4.64 |
2.98 |
3.03 |
1.73 |
| CPT1 |
7.70 |
7.64 |
18.30 |
3.54 |
3.66 |
4.12 |
3.16 |
10.21 |
7.52 |
4.15 |
3.32 |
2.35 |
| CPT2 |
8.56 |
9.58 |
16.31 |
3.87 |
3.60 |
5.78 |
0.89 |
1.36 |
6.49 |
4.13 |
3.14 |
2.88 |
| CPT3 |
20.21 |
22.98 |
22.82 |
4.57 |
4.24 |
3.62 |
9.71 |
11.34 |
16.82 |
3.16 |
3.73 |
1.73 |
| CPT4 |
28.40 |
30.20 |
29.32 |
5.15 |
6.15 |
1.49 |
18.34 |
20.10 |
23.91 |
2.86 |
2.84 |
2.14 |
| CPT5 |
36.06 |
38.60 |
38.72 |
5.17 |
5.60 |
2.20 |
24.56 |
26.83 |
28.84 |
2.47 |
3.38 |
1.91 |
| CPT6 |
39.39 |
42.83 |
43.18 |
4.30 |
4.62 |
3.75 |
27.31 |
30.29 |
32.04 |
2.90 |
3.73 |
2.23 |
| RP1 |
35.79 |
38.60 |
42.20 |
5.27 |
4.67 |
4.80 |
24.09 |
27.87 |
27.85 |
2.71 |
3.48 |
2.61 |
| RP2 |
32.09 |
31.23 |
36.65 |
6.64 |
5.16 |
4.47 |
19.93 |
25.49 |
24.41 |
3.35 |
3.74 |
2.22 |
| RP3 |
25.97 |
26.03 |
31.75 |
5.68 |
5.50 |
4.00 |
16.69 |
18.37 |
19.62 |
3.04 |
3.84 |
3.18 |
| RP4 |
21.84 |
21.50 |
25.34 |
5.36 |
5.65 |
2.92 |
13.60 |
15.34 |
16.02 |
3.16 |
3.82 |
2.84 |
| RP5 |
18.16 |
17.67 |
19.81 |
5.31 |
4.85 |
2.57 |
12.40 |
12.10 |
12.68 |
3.04 |
3.10 |
2.99 |
| RP6 |
16.11 |
15.78 |
16.97 |
4.49 |
4.38 |
1.68 |
10.79 |
11.10 |
11.09 |
3.20 |
2.71 |
2.72 |
| RP7 |
14.83 |
14.55 |
15.90 |
3.73 |
4.37 |
1.58 |
8.04 |
12.81 |
11.44 |
2.59 |
2.66 |
2.59 |
| RP8 |
13.71 |
12.40 |
16.55 |
3.80 |
3.67 |
1.98 |
8.26 |
10.90 |
10.98 |
3.29 |
2.75 |
1.79 |
| RP9 |
12.59 |
12.25 |
18.04 |
3.83 |
3.38 |
2.17 |
6.76 |
10.14 |
12.08 |
3.11 |
2.99 |
2.36 |
| RP10 |
9.06 |
12.00 |
15.18 |
2.98 |
3.86 |
2.63 |
5.95 |
10.23 |
12.16 |
3.47 |
2.99 |
2.64 |
| RP11 |
10.23 |
12.78 |
13.37 |
2.58 |
3.72 |
2.73 |
7.45 |
10.24 |
12.82 |
2.42 |
2.62 |
2.38 |
| RP12 |
10.90 |
12.94 |
14.80 |
2.89 |
3.04 |
2.93 |
7.04 |
10.61 |
12.76 |
3.19 |
3.18 |
2.62 |
| RP13 |
10.04 |
11.61 |
16.50 |
3.04 |
2.74 |
2.47 |
6.49 |
12.07 |
9.99 |
2.90 |
2.95 |
2.94 |
| RP14 |
8.90 |
12.14 |
13.94 |
2.90 |
3.26 |
2.53 |
5.72 |
8.90 |
9.75 |
3.19 |
3.04 |
1.67 |
| RP15 |
9.30 |
12.54 |
16.81 |
3.12 |
2.76 |
1.97 |
4.38 |
11.49 |
8.88 |
3.33 |
2.78 |
1.70 |
| RP16 |
8.99 |
10.44 |
13.04 |
2.50 |
1.71 |
2.86 |
5.96 |
11.91 |
9.58 |
2.28 |
2.87 |
1.76 |
| RP17 |
9.30 |
11.80 |
12.77 |
2.69 |
2.30 |
3.38 |
5.79 |
9.37 |
10.08 |
3.29 |
2.70 |
2.12 |
| RP18 | 9.66 | 12.08 | 10.03 | 2.33 | 2.53 | 3.43 | 6.17 | 8.93 | 11.50 | 2.43 | 3.06 | 2.57 |