Table 2.
Simulation parameters of the subunit specific model
| P0 simulation | HCN1/4 simulation | |||
|---|---|---|---|---|
|
Parameter |
HCN fast |
HCN slow |
HCN1 |
HCN4 |
|
V½ (mV) |
−67.1 |
−65 |
as HCN fast |
−80 |
|
k |
−9.4 |
−11.8 |
as HCN fast |
−14 |
|
gmt |
0.47 |
0.506 |
as HCN fast |
0.616 |
|
aNt (s-1) |
6.9E-3 |
4.4E-4 |
as HCN fast |
8.1E-4 |
| z |
1.71 |
2.027 |
as HCN fast |
2.13 |
|
Vh (mV) |
−62 |
−61 |
as HCN fast |
−80 |
|
Vrev (mV) |
−36 |
−36 |
−25 |
−25 |
|
ĝh (S/cm2) |
10.6E-6 |
9.4E-6 |
2.2E-4 |
6.9E-4 |
|
Vrevleak (mV) |
−5 |
5 |
|
|
|
ĝleak (S/cm2) |
1.27E-5 |
6.18E-4 |
|
|
| T (°C) | 32 | 24 |