Table 7.
Cox proportional hazard models (59 patients without lymph node metastasis)
| Variable | Crude HR | 95% CI | P value | AHR | 95% CI | P value |
|---|---|---|---|---|---|---|
| PIK3CA amplification |
2.83 |
1.08-7.36 |
0.003 |
3.13 |
1.16-8.4 |
0.024 |
| Mutation (PIK3CA K-Ras) |
0.73 |
0.09-5.6 |
0.77 |
0.83 |
0.1-6.78 |
0.86 |
| Age |
0.97 |
0.93-1.00 |
0.13 |
0.95 |
0.91-1.0 |
0.075 |
| Gender |
1.22 |
0.52-2.84 |
0.64 |
1.06 |
0.42-2.65 |
0.89 |
| Smoking status | 1.01 | 0.99-1.03 | 0.08 | 1.02 | 0.99-1.04 | 0.06 |
Adjusted for age, gender, smoking status, mutation status.
HR, hazard ratio; CI, confidence interval; AHR, adjusted hazard ratio.
Cox proportional hazard models were computed to determine the significance of PIK3CA amplification with adjustment for age, gender, smoking status and mutation status.