Figure 3. Electrostatic surface representation of LppGT and ScEF1A.

Left-hand panel: LppGT has a negatively charged binding groove, which may interact with the positively charged loop on ScEF1A (PDB code 2B7B [37]) that carries the acceptor serine. Tyr⁴⁵⁴, in the putative binding groove on LppGT, and the acceptor serine (Ser⁵³) on ScEF1A are indicated by arrows. Right-hand panel: higher magnification representation of the putative interaction site between LppGT and ScEF1A. The surface of LppGT and ScEF1A are represented in brown and green respectively. Tyr⁴⁵⁴ and Ser⁵³ are shown as sticks in pink; charged residues are in yellow (including some other residues forming the loop in which Ser⁵³ is localized, such as Gly⁵² and Phe⁵⁴).