Table 1.

Impact of checkpoint kinase 2-small interfering RNA (CHK2-siRNA) on G₂/mitotic (M) phase arrest in A549 cells treated with CpG oligodeoxynucleotide plus X-rays

Group	G2/M	G1	S
Control	13.12 ± 0.56	65.43 ± 0.87	21.45 ± 0.37
CpG	14.23 ± 0.65	66.18 ± 0.54	19.59 ± 0.41
X-ray	23.54 ± 0.67*	67.89 ± 0.78	8.57 ± 0.35
CpG + X-ray	34.56 ± 0.19**	57.83 ± 0.25	7.61 ± 0.26
CHK2-siRNA + CpG + X-ray	10.09 ± 0.23	55.38 ± 0.73	34.53 ± 0.14

Notes:

^*The G₂/M phase difference between the X-ray group and CpG + X-ray group was significant at the 0.05 level (t = −17.32, P < 0.01).

^**The G₂/M phase difference between the CpG + X-ray group and CHK2-siRNA + CpG + X-ray group was significant at the 0.05 level (t = −26.84, P < 0.01).

Abbreviation: S, synthesis phase.