TABLE 3—
Risk Profiles for Lifetime Prescription Opioid Injectors and Lifetime Cocaine Injectors: Social Networks Among Appalachian People (SNAP) Study, 2008–2010
| Prescription Opioid Injectors, ORa (95% CI) | Cocaine Injectors, ORa (95% CI) | |
| Injection risk behaviors | ||
| Years injecting (categorical) | ||
| < 1 (Ref) | 1.00 | 1.00 |
| 1–2 | 1.15 (0.26, 4.99) | 2.16 (0.99, 4.72) |
| 1–3 | 2.76 (0.33, 22.9) | 1.72 (0.71, 4.15) |
| 1–5 | 0.52 (0.16, 1.63) | 3.61** (1.62, 8.04) |
| ≥ 5 | 0.54 (0.21, 1.41) | 4.85** (2.70, 8.71) |
| Syringe sharing (prior 6 mo) | 6.87** (1.61, 29.4) | 2.26** (1.26, 4.07) |
| Cottons/cookers/water sharing (prior 6 mo) | 7.66** (2.34, 25.1) | 2.21** (1.34, 3.65) |
| Drug network characteristics | ||
| Degree centralityb | 1.77 (0.62, 5.06) | 3.15** (1.63, 6.10) |
| Eigenvector centralityc | 1.11* (1.01, 1.23) | 1.05* (1.00, 1.12) |
| k-corenessd | 1.53* (1.07, 2.20) | 1.56** (1.20, 2.03) |
Note. CI = confidence interval; OR = odds ratio.
a
Adjusted for recruiter characteristics.
b
Degree centrality takes into account the number of links to and from a person.
c
Eigenvector centrality extends the notion of degree centrality to take into account second-order connections.
d
k-coreness is a subset of the network in which each node within the k-core is connected to at least k other people.
*P < .05; **P < .01.