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. Author manuscript; available in PMC: 2012 Dec 10.
Published in final edited form as: Science. 2011 Nov 25;334(6059):1069–1070. doi: 10.1126/science.1215480

Figure 1. Selective autophagy of paternal mitochondria.

Figure 1

(A) The C. elegans hermaphrodite reproductive tract is shown. (B) Fusion of sperm and oocyte in the C. elegans spermatheca transfers the paternal nucleus, membranous organelles (MOs), and mitochondria to the (C) cytoplasm of the fertilized oocyte. MOs in the vicinity of the paternal mitochondria are labeled with ubiquitin (Ub) chains for degradation. Both MOs and paternal mitochondria are selectively recruited to autophagosomes (LGG-1/2–labeled membranes), which fuse with lysosomes.