Figure 9. Vitamin B2 improved motility of B. malayi worms and microfilarial production following doxycycline treatment.

Adult female B. malayi were cultured in the absence (control) or presence of 0.5 µM doxycycline, or antibiotic supplemented with either 2 µg/mL or 10 µg/mL vitamin B2. The motility of worms in vitro was examined daily for 7 days (A). Microfilariae production was determined at day 7 by counting the number of microfilaria present in 1 mL spent culture medium (B). Data obtained from triplicate samples (4 worms in each sample) are expressed as a mean ± standard deviation.