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(Upper left) Polyhemoglobin (PolyHb) formed by nanobiotechnological assembling of hemoglobin (Hb) molecules into soluble nanodimension complex. (Upper right) Soluble PolyHb-catalase (CAT) containing Hb and CAT. (Lower left) Soluble PolyHb-CAT-superoxide dismutase (SOD) containing Hb, CAT, and SOD. (Lower right) PolyHb-tyrosinase as oxygen carrier that also remove tyrosine to inhibit the growth of melanoma (Reprinted with permission from Ref 5. Copyright 2007 Taylor & Francis).
