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Effect of superoxide on the stability of: (Upper) PolyHb; (Lower left) crosslinked hemoglobin (Hb) and enzymes obtained directly from red blood cell (RBC) hemolysate; (Lower right) crosslinked Hb and enzymes obtained directly from RBC hemolysate but with more enzymes extracted from RBCs added. (Reprinted with permission from Ref 21. Copyright 2009 Taylor & Francis).
