. Author manuscript; available in PMC: 2012 Dec 10.

Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010 Jul-Aug;2(4):418–430. doi: 10.1002/wnan.95

TABLE 2.

Analysis of Results

Preparation	Max Hb (g/dl)	Time to 1.67 g/dl (h)
Preparation	Max Hb (g/dl)	Rats	Human
PolyHb-10	3.10	10.4	17
PolyHb-17	3.35	14.0	24
Nanocap-10-1-5K	3.05	12.3	21
Nanocap-17-1-5K	3.58	17.1	29
Nanocap-17-1.5-5K	3.60	20.0	34
Nanocap-17-1-5K-XL	3.60	20.3	35
Nanocap-17-1-15K	3.57	21.2	36
Nanocap-17-1.5-15K	3.65	23.3	39.9
Nanocap-17-1.5-15K-XL	3.66	24.2	41.5

The numbers 10 or 17 are the ratios of molecular glutaraldehyde: Hb used in the preparation of PolyHb. 1 or 1.5 are the original and 1.5 times the original amount of copolymer used. 5K and 15K are the molecular weights of the copolymer used. XL is the crosslinking of nanocapsules after their formation to increase their stability further. The results obtained from rats are from actual experiments carried out in rats. These results are then extrapolated to human as described in the text of this article. (Reprinted with permission from Ref 5. Copyright 2007 Taylor & Francis).