Table 3. Chemokine and cytokine profile in IL-4-stimulated macrophages.
| Symbol |
Description |
Fold change |
|
|---|---|---|---|
| WT | Arf−/− | ||
| Ccl11 |
Chemokine (C-C motif) ligand 11 |
0,98 |
2,14 |
| Ccl12 |
Chemokine (C-C motif) ligand 12 |
48,86 |
11,83 |
| Ccl17 |
Chemokine (C-C motif) ligand 17 |
12,97 |
13,60 |
| Ccl2 |
Chemokine (C-C motif) ligand 2 |
2,24 |
1,74 |
| Ccl22 |
Chemokine (C-C motif) ligand 22 |
1,51 |
3,52 |
| Ccl24 |
Chemokine (C-C motif) ligand 24 |
7,80 |
6,73 |
| Ccl5 |
Chemokine (C-C motif) ligand 5 |
1,57 |
2,01 |
| Ccl6 |
Chemokine (C-C motif) ligand 6 |
6,50 |
5,51 |
| Ccl7 |
Chemokine (C-C motif) ligand 7 |
21,92 |
11,05 |
| Ccl8 |
Chemokine (C-C motif) ligand 8 |
5,14 |
2,30 |
| Ccl9 |
Chemokine (C-C motif) ligand 9 |
3,71 |
3,21 |
| Ccr3 |
Chemokine (C-C motif) receptor 3 |
2,94 |
5,55 |
| Ccr4 |
Chemokine (C-C motif) receptor 4 |
0,45 |
0,40 |
| Ccr5 |
Chemokine (C-C motif) receptor 5 |
4,54 |
4,72 |
| Cxcl9 |
Chemokine (C-X-C motif) ligand 9 |
26,43 |
4,50 |
| Il6st |
Interleukin 6 signal transducer |
3,15 |
2,55 |
| Ltb |
Lymphotoxin B |
3,56 |
1,36 |
| Tnfrsf1b | Tumor necrosis factor receptor superfamily, member 1b | 2,79 | 1,53 |
Peritoneal macrophages from wild type (WT) and Arf−/− mice were stimulated with 20 ng/mL interleukin-4 (IL-4) for 6 h, and the expression of pro-inflammatory genes was analyzed by RT2 PCR analysis. Genes upregulated in IL-4 stimulated Arf−/− cells as compared with WT cells are shown in bold.