Table 2. Cells currently known to express granzyme B.
| Cell type | Perforin co-expression |
|---|---|
| Articular chondrocytes94 |
Yes |
| B cells9,10,36 |
No |
| Basophils33 |
No |
| B-CLL cells39 |
No |
| Breast carcinoma cells37 |
? |
| CD34+ hematopoietic stem cells28 |
Yes |
| CTL and NK cells93 |
Yes |
| Keratinocytes29 |
No/yes |
| Macrophages96 |
? |
| Mast cells34 |
No/yes |
| Mesenchymal stromal cells (unpublished observation) |
No |
| Monocyte-derived dendritic cells51 |
? |
| Neutrophils35 |
Yes |
| Plasmacytoid dendritic cells31,32 |
No |
| Platelets97 |
? |
| Regulatory T cells95 |
Yes |
| Testicular Sertoli cells and placental syncytial trophoblasts30 |
No |
| Urothelial carcinoma cells38 | No |
B-CLL, B-cell chronic lymphocytic leukemia; CTL, cytotoxic T lymphocyte; NK, natural killer.