Figure 1. Genes specific to T-cell and myeloid lineages significantly associated with survival. Genes significantly associated with survival were found to be enriched for genes specific to myeloid cells (21 genes, all with hazard ratio, HR, > 1) and T cells (15 genes with HR > 1, 8 genes with HR < 1), indicating an association of those lineages with the survival signature. While our samples were derived from the peripheral blood, 6 T cell-specific genes have also been found by other studies to be differentially expressed in lung adenocarcinoma tumor samples, reflecting the infiltration of T cells into lung lesions. These are shown in the T cell overlap with the lung. Cytokines and chemokines detected in the serum of lung cancer patients that can promote or interfere with immune responses are also indicated.