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. Author manuscript; available in PMC: 2013 Dec 15.
Published in final edited form as: J Immunol. 2012 Nov 9;189(12):5622–5631. doi: 10.4049/jimmunol.1200709

Figure 3. In vitro differentiated central but not effector memory CD8+ T cell rejection of skin grafts is enhanced by a local inflammatory stimulus.

Figure 3

Rag1−/−mice bearing two well-healed K5mOVA grafts received either in vitro differentiated TCM (black lines) or TEM (grey lines). Grafts were then treated with either imiquimod or control cream and graft rejection plotted on a Kaplan-Meier survival curve. A. 104 adoptively transferred TCM and TEM CD8 T cells. Data analysed by log rank test, n=7 for each group, *p<0.05, ns = not significant. B. 105 adoptively transferred TCM and TEM CD8 T cells. Data analysed by log rank test, n=7 for each group, **p<0.01, ns = not significant. C. 106 adoptively transferred TCM and TEM CD8 T cells. Data analysed by log rank test, n=8 for each group, **p<0.01, ns = not significant.