Table 3.

Risk of distal gastric cancer by number of sero-positives to 6 H. pylori proteins (Omp, HP0305, HyuA, HpaA, CagA, and VacA) for each individual, in the SMHS

All				Excluding cases diagnosed within 2 years after recruitment and matched controls
No. sero-positive	Cases n (%)	Controls n (%)	Matched OR* (95% CI)	Cases n (%)	Controls n (%)	Matched OR* (95% CI)
All
0–3	29 (12.8)	114 (25.3)	1.00 (Reference)	17 (10.8)	85 (26.9)	1.00 (Reference)
4–5	141 (62.4)	273 (60.5)	2.08 (1.31, 3.30)	105 (66.5)	188 (59.5)	2.79 (1.56, 4.96)
6	56 (24.8)	64 (14.2)	3.49 (2.00, 6.11)	36 (22.8)	43 (13.6)	4.16 (2.08, 8.32)
P for trend			<0.0001			<0.0001

^*odds ratios from a conditional logistic regression model, cases and controls matched on age (within 2 years), date (within 30 days) and time (morning or afternoon) of sample collection, time interval since last meal (within 2 hours), and antibiotic use in the past week (yes/no).