Table 6.

Pre-transplant Symptom Distress Means and Standard Deviations and Post-transplant Ridit Effect Size Difference Scores (with FDR^b adjusted posterior probabilities)

Symptom Measure	Pre Mean	Pre SD	1 Month	FDRb	3 Month	FDR	6 Month	FDR	9 Month	FDR	12 Month	FDR
SOB @ rest	1.89	1.33	−0.28	0.0683	−0.44	0.0007	−0.63	<.0001	−0.64	<.0001	−0.48	0.0003
SOB w/activity	2.53	1.3	−0.50	0.0001	−0.57	<.0001	−0.59	<.0001	−0.74	<.0001	−0.52	0.0001
Fatigue	1.91	1.25	−0.29	0.0591	−0.31	0.0217	−0.36	0.0085	−0.46	0.0007	−0.27	0.0627
Chest tightness	1.39	1.22	−0.09	0.589	−0.23	0.0939	−0.45	0.0007	−0.41	0.0029	−0.3	0.0481
Coughing	1.42	1.28	−0.15	0.3845	−0.08	0.6171	−0.09	0.5299	−0.25	0.0799	−0.21	0.1565
Difficulty clearing secretions	1.35	1.29	0.001	0.9947	−0.10	0.5475	−0.23	0.1051	−0.3	0.036	−0.42	0.0018
Wheezing	1.26	1.28	−0.21	0.1662	−0.17	0.2382	−0.24	0.1023	−0.37	0.0088	−0.24	0.0886
Heart palpitations	0.73	1.08	−0.05	0.7725	−0.24	0.0818	−0.31	0.024	−0.24	0.0872	−0.1	0.4854
Chest pain	0.48	0.97	0.061	0.7523	0.015	0.9437	−0.03	0.8261	−0.06	0.6554	0.05	0.7556
Infections of finger/toenails	0.31	0.89	0.119	0.4973	0.074	0.6901	0.054	0.7329	0.043	0.7733	0.029	0.8459
Excessive hair growth	0.41	1.05	0.052	0.7725	0.147	0.3319	0.176	0.2498	0.05	0.7361	0.156	0.3192
Excessive hair loss	0.6	1.27	0.067	0.722	0.039	0.8599	0.158	0.303	0.208	0.1616	0.155	0.3257
Acne	0.46	0.95	−0.03	0.8343	−0.07	0.7098	−0.03	0.8261	−0.05	0.7156	−0.01	0.898
Fragile skin	0.67	1.16	0.114	0.52	−0.00	0.9691	0.082	0.5922	0.134	0.37	0.073	0.6229
Bruising easily	0.64	1.05	0.226	0.1564	0.156	0.2984	0.563	<.0001	0.243	0.0873	0.203	0.1751
Swollen ankles	0.65	1.03	0.196	0.2235	0.069	0.7108	0.159	0.3014	0.167	0.2521	0.255	0.0837
Changes in facial appearance	0.76	1.21	0.098	0.589	0.155	0.3028	0.107	0.508	0.127	0.3892	0.122	0.4244
Changes in bodily appearance	0.85	1.21	0.087	0.6246	0.047	0.8123	0.163	0.2969	0.071	0.6361	0.11	0.4504
Nausea/upset stomach	0.53	0.88	0.506	0.0001	0.588	<.0001	0.404	0.0029	0.239	0.0925	0.25	0.0855
Vomiting	0.39	0.89	0.274	0.0841	0.374	0.0043	0.314	0.024	0.254	0.0786	0.185	0.217
Stomach pain	0.46	0.85	0.40	0.0036	0.47	0.0003	0.245	0.1023	0.251	0.0799	0.265	0.0744
Bloated feeling in stomach	0.78	1.11	0.195	0.2235	0.202	0.1662	−0	0.984	0.064	0.665	0.15	0.3346
Constipation	0.49	0.91	0.314	0.0415	0.246	0.0818	0.106	0.508	0.012	0.9425	0.032	0.8347
Diarrhea	0.46	0.81	0.149	0.3913	0.264	0.0635	0.178	0.2448	0.118	0.4265	0.224	0.1281
Changes in taste sensation	0.34	0.84	0.499	0.0001	0.317	0.0211	0.175	0.2498	0.132	0.372	0.076	0.6127
Weight loss	0.67	1.06	0.205	0.2049	−0.05	0.7799	−0.09	0.535	−0.25	0.0786	−0.29	0.0493
Weight gain	0.88	1.31	−0.05	0.7725	−0.01	0.9376	0.164	0.2969	0.222	0.1238	0.258	0.0804
Overeating	0.68	1.2	0.075	0.6791	0.012	0.9459	0.131	0.4123	0.188	0.2033	0.182	0.2266
Feeling hungry all the time	0.6	1.15	0.165	0.3304	0.157	0.2984	0.113	0.4947	0.18	0.2116	0.194	0.1945
Poor appetite	0.71	1.06	0.245	0.1324	0.032	0.876	−0.1	0.5121	−0.24	0.0853	−0.29	0.0493
Urinating less than usual	0.24	0.73	0.146	0.3982	0.1	0.5502	0.095	0.535	−0.03	0.8303	0.169	0.2708
Urinating more than usual	0.53	1.08	0.022	0.8753	0.17	0.258	0.108	0.508	0.118	0.4295	0.177	0.2416
Decreased interest in sex	1.15	1.14	0.052	0.7725	−0.11	0.5258	−0.2	0.182	−0.17	0.2521	−0.13	0.4089
Increased interest in sex	0.38	0.99	0.008	0.9603	−0.06	0.7615	−0.14	0.3767	−0.01	0.9425	−0.11	0.4448
Decreased sexual performance	1.38	1.48	−0.02	0.8524	−0.22	0.1379	−0.25	0.1023	−0.22	0.1523	−0.12	0.4244
Muscle weakness in whole body	1.35	1.46	0.166	0.3304	−0.02	0.9096	−0.09	0.5292	−0.22	0.1224	−0.11	0.4448
Muscle weakness in arms or legs	1.45	1.45	0.234	0.149	−0	0.9764	−0.03	0.8261	−0.19	0.1779	−0.1	0.4504
Trouble concentrating	1.25	1.46	−0.04	0.7748	−0.1	0.5435	−0.11	0.4818	−0.18	0.2105	−0.07	0.6208
Poor vision even with glasses	0.93	1.36	0.123	0.4955	0.189	0.2004	0.132	0.4123	0.062	0.6714	0.131	0.3978
Dizziness	0.84	1.24	0.19	0.2336	0	0.9953	−0.09	0.5414	−0.05	0.7156	−0	0.9825
Cold hands or feet	0.62	1	0.121	0.4973	−0	0.9953	0.093	0.535	0.028	0.8535	−0.11	0.4448
Cramps in hands/feet/legs	1.02	1.31	−0.15	0.3821	−0.03	0.8688	0.023	0.8877	−0	0.9641	0.023	0.882
Burning, throbbing, or numbness in hands or feet	0.56	1.15	0.165	0.3304	0.279	0.0458	0.302	0.0323	0.148	0.3178	0.283	0.0575
Tiring easily	2.01	1.34	−0.18	0.2493	−0.31	0.0219	−0.33	0.0167	−0.41	0.0029	−0.32	0.0301
Sleepiness	1.36	1.35	0.111	0.5389	−0.11	0.489	−0.15	0.303	−0.11	0.4446	−0.19	0.1945
Problems falling asleep	1.15	1.35	0.256	0.1066	0.096	0.5687	−0	0.9787	−0.18	0.2089	−0.11	0.4396
Not feeling rested after sleeping	1.18	1.24	0.10	0.589	−0.02	0.9003	−0.1	0.508	−0.09	0.5109	−0.15	0.306
Frequent nightmares	0.42	1.04	0.195	0.2235	0.101	0.5502	−0.1	0.518	−0.01	0.941	0.001	0.9915
Problems remembering things	1.34	1.46	−0.17	0.291	−0.22	0.1222	−0.13	0.3815	−0.09	0.5176	−0.07	0.6348
Confusion or disorientation	0.71	1.37	0.077	0.6744	−0.03	0.876	−0.1	0.518	−0.1	0.5029	0.021	0.8868
Tremors	0.56	1.16	0.472	0.0003	0.426	0.0012	0.405	0.0029	0.265	0.0698	0.237	0.1047
Headaches	0.94	1.15	−0.07	0.6791	0.16	0.2949	−0.03	0.8261	−0.06	0.6554	0.032	0.8347
Fever	0.67	1.21	0.05	0.7725	−0.05	0.7799	−0.05	0.7329	−0.13	0.372	−0.11	0.4396
Feeling restless	0.87	1.09	0.134	0.4608	−0.08	0.6351	−0.15	0.303	−0.12	0.4238	−0.04	0.7978
Feeling depressed	1.18	1.23	−0.20	0.2049	−0.26	0.0656	−0.18	0.2237	−0.31	0.0311	−0.16	0.306
Mood swings	0.8	1.15	0.05	0.7725	−0.06	0.7615	−0.07	0.6081	−0.13	0.3548	−0.1	0.4854
Feeling nervous or apprehensive	0.92	1.24	0.106	0.5549	−0.09	0.563	−0.07	0.6081	−0.2	0.1626	−0.12	0.4183
Feeling afraid	0.79	1.18	0.023	0.8723	−0.23	0.1023	−0.21	0.1414	−0.28	0.047	−0.24	0.099
Feeling sad	0.94	1.11	−0.13	0.4624	−0.27	0.0458	−0.15	0.3014	−0.28	0.045	−0.14	0.3691
Feeling helpless	1.26	1.43	−0.12	0.4852	−0.31	0.0219	−0.35	0.01	−0.4	0.0032	−0.3	0.0445
Feeling lack of control over your life	1.47	1.56	−0.08	0.6246	−0.34	0.009	−0.33	0.0151	−0.49	0.0003	−0.38	0.0055
Increased irritability	0.8	1.07	−0.10	0.5549	−0.19	0.1969	−0.16	0.3005	−0.33	0.0189	−0.23	0.1115
Problems keeping temper under control	0.54	1.08	0.081	0.6558	−0.03	0.8599	0.035	0.8261	−0.12	0.3847	−0.14	0.3414
Feeling less masculine/feminine	0.81	1.21	−0.08	0.6246	−0.22	0.1222	−0.2	0.1617	−0.17	0.2213	−0.14	0.3414

^a= negative (−) effect size changes indicate improvement from pre transplant symptom mean, while positive effect sizes indicate increases in new symptoms

^bFDR = False Discovery Rate