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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Curr Opin Chem Biol. 2012 Nov 8;16(5-6):544–552. doi: 10.1016/j.cbpa.2012.10.015

Figure 3.

Figure 3

Bacteria hijack host prenylation machinery during infection. Upon bacterial entry via phagocytosis (1), the infectious bacterium is surrounded by a vacuole and immediately secretes effectors into the host cytosol (2). Effectors containing a CaaX box may be prenylated and further modified by other enzymes implicated in the prenylation pathway (3). These modifications may help target bacterial effectors to the cytosolic face of the bacteria-containing vacuole or elsewhere in the host cell (4).