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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Mech Ageing Dev. 2012 Aug 30;133(11-12):637–646. doi: 10.1016/j.mad.2012.08.004

Table 1.

The effect of to expression on female life span.

Driver Mean LS
(vs. ctrl)		 Mean LS
extension		 Median
LS (vs
ctrl)		 Median
LS
extension		 Max
LS (vs.
ctrl)		 Max LS
extension		 Number of
flies
(control;
experimental)		 χ2 p-value
to-Gal4 51/43 19% 54/44 23% 72/66 9% 196
217		 45.81 <0.0001
to-Gal4 47/39 21% 48/36 33% 68/64 6% 238
250		 25.89 <0.0001
to-Gal4 + MP 36/36 0% 36/36 0% 56/56 0% 269
252		 0.714 0.3981
S1-106, 100µM 55/55 0% 56/56 0% 74/75 −1% 234
251		 0.1583 0.6907
S1-106, 500µM 61/55 11% 64/56 14% 82/75 9% 234
229		 41.31 <0.0001
S1-32, 100µM 52/52 0% 54/54 0% 80/78 3% 231
243		 0.9353 0.3335
S1-32, 500µM 66/52 27% 72/54 33% 83/80 4% 231
141		 39.16 <0.0001
S1-32, 100µM 44/41 7% 48/42 14% 66/62 7% 232
227		 7.14 0.0075
S1-32, 500µM 59/41 44% 64/42 52% 79/62 27% 232
185		 148.5 <0.0001
S1-32 60/48 25% 62/48 29% 82/68 21% 220
221		 94.18 <0.0001
S1-32 + MP 41/32 28% 36/32 12% 50/51 −2% 238
221		 6.251 0.0124

Log rank analysis of the survivorship curves of female flies. Mean, median and maximum lifespan, log rank analysis, p-value, percent change in mean, median and maximum lifespan as compared to controls (without RU486 for GeneSwitch experiments), Chi-square and p-values derived from the survivorship curves for each indicated intervention are shown. Maximum life span was calculated as the median life span of the longest surviving 10% of the population.