Table 3.
Number (%) of Patients with Each Condition Post-Study.
| N (%) of Patients | |||||||
|---|---|---|---|---|---|---|---|
| DFMO (N=108) | Placebo (N=108) | All (N=209) | p-valuea | ||||
| Hematological Malig. | 4 | (3.7) | 2 | (2.0) | 6 | (2.9) | 0.684 |
| Prostate Cancer | 5 | (4.6) | 2 | (2.0) | 7 | (3.3) | 0.447 |
| Noninvasive Neoplasm | 23 | (21.3) | 28 | (27.7) | 51 | (24.4) | 0.334 |
| Cardiacb | 23 | (21.3) | 22 | (21.8) | 45 | (21.5) | 1.000 |
| Vascular Disease | 22 | (20.4) | 20 | (19.8) | 42 | (20.1) | 1.000 |
| Diabetes Mellitus Type 2 | 8 | (7.4) | 5 | (5.0) | 13 | (6.2) | 0.572 |
| Neurological Disorders | 22 | (20.4) | 17 | (16.8) | 39 | (18.7) | 0.595 |
| Colonic Polyps | 16 | (14.8) | 11 | (10.9) | 27 | (12.9) | 0.418 |
| Renal Diseasec | 4 | (3.7) | 2 | (2.0) | 6 | (2.9) | 0.684 |
| Hepatic Disordersd | 9 | (8.3) | 3 | (3.0) | 12 | (5.7) | 0.137 |
| Eye Disorders | 7 | (6.5) | 7 | (6.9) | 14 | (6.7) | 1.000 |
| Death | 10 | (9.3) | 6 | (5.9) | 16 | (7.7) | 0.441 |
a
Fisher’s exact test
b
Chronic Heart Failure, valve disorders, CAD, abnormal ECG, endocarditis, abnormal heart rate, cardiomegaly.
c
Chronic Renal Failure, abnormal creatinine, kidney cyst, calculus
d
Hepatitis, cholecystitis, hepatic cyst, abnormal LFTs, ascites, microalbumin, common bile duct obstruction.