Mice were treated as in Figure 1, followed by brain microvessel isolation. mRNA levels of TNF-α (A), IL-1β (B), ICAM-1 (C), and VCAM-1 (D) were determined by real-time PCR. Results are mean ± SEM, n=6. *Significantly different as compared to control groups at **p<0.01 or ***p<0.001. †Results in the PCB153-NPs group are statistically different from those in the PCB153 group at †p<0.05, ††p<0.01, or †††p<0.001.