Skip to main content
. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Metabolism. 2012 Sep 12;62(1):152–162. doi: 10.1016/j.metabol.2012.07.012

Figure 6.

Figure 6

C2 and C5 regions of 13C NMR spectrum of MAG derived from plasma glucose of a high-fat-fed animal. Relative peak area of D12 is bigger than that of D56 while C2Q is smaller than C5Q (A). The 13C asymmetry in glucose could be the activity of pentose phosphate pathway (PPP, B). MAG C5 resonance (rather than C2) was used in the analysis of fluxes associated with the citric acid cycle because the labeling at glucose C4-C6 remains the same even in the presence of PPP activity, reflecting the labeling of oxaloacetate C1-C3. See the text for the details. Abbreviations: D12, doublet due to J12; D23, doublet due to J23; Q, doublet of doublets, or quartet, arising from coupling of carbon 2 with both carbons 1 and 3 or from coupling of carbon 5 with both carbons 4 and 6; D45, doublet due to J 45; D56, doublet due to J56; S, singlet resonance; open circle=12C; filled circle=13C.