Skip to main content
. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Liver Int. 2012 Nov 1;33(1):149–161. doi: 10.1111/liv.12016

Figure 5. Activated Sinusoidal Endothelial cells and Myofibroblasts are Hedgehog responsive in schistosomiasis mansoni.

Figure 5

Double immunohistochemistry for Gli2 (brown) and CD31 (blue) (A) and for Gli2 (brown) and αSMA (blue) (B) in representative liver sections from subjects with pattern A (left) or with pattern Ec fibrosis (middle). Final magnification ×400, insert ×600. C) Quantification of the immunostaining for Gli2/CD31 (left) and for Gli2/αSMA (right) from selected patients. (Normal=2 subjects, Pattern A=2, Ec=8 (Gli2/CD31) or 5 (Gli2/αSMA)). Results were normalized to the number of double positive cells in normal individuals; means ± S.E.M. are displayed. *p<0.05; **p<0.001.