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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Genes Immun. 2012 Sep 20;13(8):605–620. doi: 10.1038/gene.2012.39

Table 3.

Contribution of age, gender and -2518 MCP-1 -1607 MMP-1 two-locus genotypes in TB disease severity

Number of observations = 224
LR chi-square (5) = 68.62
Probability > chi2 = 0.00001
Log likelihood = −119.87
Pseudo R2 = 0.223
Dependent Variables OR S.E. Z Prob > |Z| 95% C.I.
Age 0.998 0.0154 − 0.10 0.921 0.969 – 1.029
Gender (female) 0.667 0.215 − 1.26 0.209 0.355 – 1.254
Group 2: A/- 2G/2G 1.358 0.571 0.73 0.467 0.595 – 3.095
Group 3: GG 1G/- 0.6 0.306 − 1.00 0.317 0.222 – 1.63
Group 4: GG 2G/2G 13.13 5.941 5.69 0.0001 5.41 – 31.88
Pearson Goodness-of-fit: Chi2 = 151.44; p = 0.13

Genotype A/- 1G/- = genotypes AA 1G/1G or AA 1G/2G, AG 1G/1G or AG 1G/2G

Genotype A/- 2G/2G = genotypes AA 2G/2G, AG 2G/2G

Genotype GG 1G/- = genotypes GG 1G/1G, GG 1G/2G

Group 1 was used as reference

OR = Odds Ratio; SE = standard error; Z = Z score; 95% C.I. = 95% confidence interval