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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Genes Immun. 2012 Sep 20;13(8):605–620. doi: 10.1038/gene.2012.39

Table 5.

Associations of the -2518 MCP-1 and -1607 MMP-1 two-locus genotypes and sputum conversion at more than 3 months

Two-locus genotypes Cases n (%) OR Prob > chi2 95% C.I.
Group 1: A/- 1G/- 5 (9.8) 1 - -
Group 2: A/- 2G/2G 9 (15.3%) 1.4 0.57 0.44 – 4.5
Group 3: GG 1G/- 6 (13.9%) 1.492 0.54 0.41 – 5.33
Group 4: GG 2G/2G 21 (29.6%) 3.864 0.009 1.3 – 11.5
Test of homogeneity (equal odds):
Score test for trend of odds:
Chi2 = 10.41, d.f. = 3; prob > chi2 = 0.0154
Chi2 = 8.61, d.f. = 1; prob > chi2 = 0.0034

Genotype A/- 1G/- = genotypes AA 1G/1G or AA 1G/2G, AG 1G/1G or AG 1G/2G

Genotype A/- 2G/2G = genotypes AA 2G/2G, AG 2G/2G

Genotype GG 1G/- = genotypes GG 1G/1G, GG 1G/2G

n = number of cases showing sputum conversion > 3 months

OR = Odds Ratio; 95% C.I. = 95% confidence interval, d.f. = degrees of freedom