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. Author manuscript; available in PMC: 2012 Dec 11.
Published in final edited form as: J Neuroendocrinol. 2009 Jan 15;21(3):217–226. doi: 10.1111/j.1365-2826.2009.01822.x

Figure 1. Acute effects of oestrogens and of aromatase inhibition on male sexual behaviour in quail and mice.

Figure 1

A. Time-response curve of the acute effects of 17β-oestradiol (E2, 500μg/kg) on consummatory behaviour assessed by mount attempt (MA) and cloacal contact movements (CCM) frequency. B. Time-response curve of the acute effects of the aromatase inhibitor, vorozole™ (30mg/kg), on appetitive (as assessed by the frequency of the rhythmic cloacal sphincter movements [RCSM]) and consummatory sexual behaviour (as assessed by the frequency of mount attempts) expressed as percentage of controls. C. Acute effect of E2 (500μg/subject) and absence of acute effect of the aromatase inhibitor, ATD (1,4,6-androstatriene-3,17-dione, 4mg/subject), on male sexual behaviour in aromatase knock-out mice (ArKO) injected 10 minutes before the test. D. Acute effect of ATD (4mg/subjects) on male sexual behaviour in wild-type mouse injected 10 minutes before the test. E. Acute effect of E2 (500μg/subject) on male sexual behaviour in wild-type mouse chronically treated with ATD (0.5mg/subject) to inhibit the genomic effects of estrogens. Redrawn from [22, 23, 41].