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Concentration and time response of Cbfa1/Runx2 mRNA downregulation by dexamethasone. Quantitation of the relative Cbfa1/Runx2 gene expression of the D1 cells treated with (a) different concentrations of dexamethasone for 48 h and (b) 10−7 mol/L dexamethasone for different time points. Error bars represent the standard deviation of triplicate experiments (*P < 0.05). (Reprinted, with permission, from: [56].)
