Table 2.
Comparison of molecular properties between RSM, RAM, RPL, and ROJ.
| Index | RSM (mean ± SD) | RAM (mean ± SD) | ROJ (mean ± SD) | RPL (mean ± SD) | ||||
|---|---|---|---|---|---|---|---|---|
| Total compounds | Active compounds | Total compounds | Active compounds | Total compounds | Active compounds | Total compounds | Active compounds | |
| nHDon | 2.09 (2.69) |
1.95 (3.88) |
4.05 (2.86) |
3.89 (2.77) |
3.22 (3.23) |
2.68 (1.49) |
5.00 (4.65) |
3.42 (2.19) |
| nHAcc | 4.23 (4.47) |
5.19 (6.78) |
7.51 (4.70) |
7.91 (4.32) |
6.72 (6.22) |
6.58 (2.46) |
8.50 (7.62) |
6.42 (3.70) |
| MLogP | 2.45 (2.61) |
2.10 (2.28) |
0.75 (2.59) |
1.18 (2.60) |
2.12 (2.48) |
1.61 (0.91) |
1.28 (3.38) |
1.44 (2.57) |
| MW | 310.37 (156.93) | 343.28 (219.76) |
411.00 (232.39) | 438.31 (169.88) |
428.72 (262.11) | 373.42 (120.83) |
484.18 (286.37) | 379.77 (92.05) |
| RBN | 3.66 (5.17) |
2.09 (4.99) |
5.17 (3.68) |
5.02 (3.42) |
4.99 (4.81) |
3.26 (1.45) |
6.58 (6.02) |
4.08 (3.96) |
| nCIC | 2.74 (1.73) |
3.72 (1.35) |
3.59 (2.66) |
4.14 (1.84) |
4.05 (3.01) |
3.74 (1.52) |
3.89 (2.6971) | 3.58 (1.38) |
| Hy | 0.56 (2.00) |
0.38 (2.79) |
1.92 (2.06) |
1.68 (1.95) |
1.13 (2.13) |
0.74 (0.97) |
2.46 (3.28) |
1.28 (1.61) |
| TPSA (Tot) | 73.61 (76.27) |
86.86 (114.01) |
120.61 (72.73) |
123.18 (69.35) |
102.76 (92.12) |
100.13 (35.49) |
142.01 (125.68) |
106.28 (59.74) |
*RSM (Radix Salviae Miltiorrhiza), RAM (Radix Astragali Mongolici), RPL (Radix Puerariae lobatae), and ROJ (Radix Ophiopogonis Japonici).