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. Author manuscript; available in PMC: 2014 Jan 21.
Published in final edited form as: Analyst. 2013 Jan 21;138(2):10.1039/c2an36128k. doi: 10.1039/c2an36128k

Table 1.

Figures of Merit Comparison for SERS and ELISA.

Parameter SERS ELISA

MMP-7 CA 19-9 MMP-7 CA 19-9
Bmaxa 14900 3810 6.14 5.77
Kd (M) 1.96×10−10 6.52×10−11 1.06×10−9 7.95×10−10
Nsa 131 130 0.0480 0.116
R2 0.989 0.991 0.999 0.999
Blank σa 2.00 3.19 0.00212 0.0113
LOD (pg/mL) 2.28 34.5 31.8 987
LOD (M) 78.6×10−15 164×10−15 1.10×10−12 4.70×10−12
a

Units for these parameters are cts s−1 for SERS and absorbance units for ELISA.