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. Author manuscript; available in PMC: 2013 Oct 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2012 Aug 10;264(2):192–201. doi: 10.1016/j.taap.2012.08.001

Fig. 6.

Fig. 6

Hepatocyte regeneration in APAP and APAP/TFP mice. A. Proliferating cell nuclear antigen (PCNA) expression was measured by immunoblot in the APAP and APAP/TFP mice. PCNA expression was increased in the APAP mice at 24 and 48 h and absent or very decreased in the APAP/TFP mice at 24 and 48 h. Densitometry of PCNA expression in APAP and APAP/TFP mice demonstrated reduced PCNA expression in the APAP/TFP mice (#p<0.05) compared to the APAP mice. B. PCNA expression by immunoblot at 72 h in an additional experiment of APAP and APAP/TFP mice. The APAP/TFP mice had reduced expression of PCNA at the 72 h time point (#p<0.05) compared to the APAP mice.