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. 2012 Feb;3(Suppl 1):19–30. doi: 10.1055/s-0031-1298605

Table 7. Single-level versus multilevel C-ADR.

Pain and disability
Outcomes Strength of evidence Conclusions/comments
1. Overall success graphic file with name ebsj03019-008.jpg Three studies reported various measures of overall success (Odom’s criteria, neurological success, composite measure) and found no statistical differences between treatment groups across 1 to 6 years of follow-up.
1. Pain graphic file with name ebsj03019-009.jpg Measured a variety of ways (VAS, analgesic use, treatment intensity score) across four studies.
Inconsistent results regarding the effectiveness of one surgery to provide better pain relief over the other.
3. NDI graphic file with name ebsj03019-008.jpg No significant differences between single-level and multilevel C-ADR in NDI scores over 1 to 6 years follow-up as reported by four studies.
4. Quality of Life
(SF-36 PCS and MCS)
graphic file with name ebsj03019-009.jpg No significant differences were reported between single-level and multilevel C-ADR at 1, 2, 4, or 6 years follow-up in two studies.
5. Patient satisfaction graphic file with name ebsj03019-009.jpg Similar numbers of patients in both treatment groups were satisfied with their treatment and would repeat the procedure as reported by one study.
6. Return to work graphic file with name ebsj03019-009.jpg Greater proportion of multilevel C-ADR patients returned to part-time or full-time work and at a quicker rate than single-level C-ADR patients in one study.
Complications
Outcomes Strength of evidence Conclusions/comments
1. Reoperation graphic file with name ebsj03019-009.jpg Reoperation was reported by three studies, one of which reported a lower rate at 2 years following single-level compared with multilevel C-ADR, and two studies reported similar reoperation rates between the groups.
2. Heterotopic ossification graphic file with name ebsj03019-009.jpg Two studies reported conflicting results for the rate of HO between groups.
3. Other complications graphic file with name ebsj03019-009.jpg A significantly lower incidence of dysphagia was reported following single-level compared with multilevel C-ADR at 2 years in one study.
Rates of revision, device subsidence or migration, infection, mortality, and other complications were similar between groups.