Table 7. Single-level versus multilevel C-ADR.
Pain and disability | ||
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Outcomes | Strength of evidence | Conclusions/comments |
1. Overall success | Three studies reported various measures of overall success (Odom’s criteria, neurological success, composite measure) and found no statistical differences between treatment groups across 1 to 6 years of follow-up. | |
1. Pain | Measured a variety of ways (VAS, analgesic use, treatment intensity score) across four studies. Inconsistent results regarding the effectiveness of one surgery to provide better pain relief over the other. |
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3. NDI | No significant differences between single-level and multilevel C-ADR in NDI scores over 1 to 6 years follow-up as reported by four studies. | |
4. Quality of Life (SF-36 PCS and MCS) |
No significant differences were reported between single-level and multilevel C-ADR at 1, 2, 4, or 6 years follow-up in two studies. | |
5. Patient satisfaction | Similar numbers of patients in both treatment groups were satisfied with their treatment and would repeat the procedure as reported by one study. | |
6. Return to work | Greater proportion of multilevel C-ADR patients returned to part-time or full-time work and at a quicker rate than single-level C-ADR patients in one study. |
Complications | ||
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Outcomes | Strength of evidence | Conclusions/comments |
1. Reoperation | Reoperation was reported by three studies, one of which reported a lower rate at 2 years following single-level compared with multilevel C-ADR, and two studies reported similar reoperation rates between the groups. | |
2. Heterotopic ossification | Two studies reported conflicting results for the rate of HO between groups. | |
3. Other complications | A significantly lower incidence of dysphagia was reported following single-level compared with multilevel C-ADR at 2 years in one study. Rates of revision, device subsidence or migration, infection, mortality, and other complications were similar between groups. |