Table 4.
Commonly Observed Toxicities (adverse events which were unlikely or not related to treatment were excluded)
| ADVERSE EVENT | Capecitabine, Gemcitabine (n=51) | |||||
|---|---|---|---|---|---|---|
| Grade
| ||||||
| 0 | 1 | 2 | 3 | 4 | 5 | |
|
|
|
|||||
| Blood/Bone Marrow | 6 | 7 | 13 | 21 | 4 | 0 |
| Cardiac Arrhythmia | 49 | 0 | 1 | 1 | 0 | 0 |
| Cardiac General | 48 | 1 | 2 | 0 | 0 | 0 |
| Constitutional symptoms | 11 | 21 | 11 | 7 | 1 | 0 |
| Dermatology/Skin | 24 | 11 | 12 | 4 | 0 | 0 |
| Gastrointestinal | 7 | 21 | 13 | 10 | 0 | 0 |
| Hemorrhage/Bleeding | 49 | 0 | 1 | 1 | 0 | 0 |
| Hepatobiliary/Pancreas | 47 | 0 | 4 | 0 | 0 | 0 |
| Infection | 44 | 0 | 5 | 2 | 0 | 0 |
| Lymphatics | 43 | 6 | 2 | 0 | 0 | 0 |
| Metabolic/Laboratory | 15 | 11 | 14 | 11 | 0 | 0 |
| Musculoskeletal/Soft Tissue | 46 | 0 | 4 | 1 | 0 | 0 |
| Neurology | 43 | 7 | 1 | 0 | 0 | 0 |
| Ocular/Visual | 48 | 3 | 0 | 0 | 0 | 0 |
| Pain | 30 | 10 | 8 | 2 | 1 | 0 |
| Pulmonary/Upper Respiratory | 45 | 4 | 2 | 0 | 0 | 0 |
| Renal/Genitourinary | 48 | 0 | 3 | 0 | 0 | 0 |
| Vascular | 48 | 0 | 2 | 0 | 1 | 0 |
| MAXIMUM GRADE ANY ADVERSE EVENT Number | 0 | 2 | 12 | 31 | 6 | 0 |