Table 1. Parameters imputed from periodic regression analysis for genes studied.
1A | CLOCK | |||||||||
Control Subcutaneous Adipose Tissue | Control Visceral Adipose Tissue | |||||||||
Population (T = 24 h) | Mesor (AU) | Amplitude (AU) | Acrophase (hh∶mm) | Percent Rhythm (%) | P | Mesor (AU) | Amplitude (AU) | Acrophase (hh∶mm) | Percent Rhythm (%) | P |
Estimated | 1.40 | 0.36 | 00:12 | 75.54 | <0.001 | 1.78 | 0.73 | 08:55 | 76.00 | <0.001 |
Lower limit | 1.27 | 0.27 | 23:13 | 1.48 | 0.55 | 07:57 | ||||
Upper limit | 1.53 | 0.45 | 01:10 | 2.08 | 0.91 | 09:54 |
Estimates of the parameters that characterize the rhythm (amplitude, acrophase and mesor) calculated for population, including the significance level and the percentage of variance explained by the rhythm of CLOCK (1A), PER2 (1B) and BMAL1 (1C) for control and dexamethasone subcutaneous and visceral human adipose tissue. Upper and lower limits (95% of confidence) are also shown. Mesor population estimates were obtained directly from the individual mesor. Population estimates for Dexamethasone groups are for a 12 h rhythm (circadian rhythm is not present). Acrophase data are referred to ZT. A negative value in the limits indicates the absence of statistically significant rhythm. AU: Arbitrary units, T: time, h: hours, m: minutes.