Figure 6. Effect of INV-315 on MPO activity in mice peritoneal macrophages and human blood.
A. MPO activity in macrophages derived from the peritoneal cavity of C57BL/6 mice. Data were derived from 5–7 mice for each group. B. Luminol-bioluminescence imaging of PMA-stimulated blood. C. Luminol bioluminescence was plotted as a function of time and concentration of INV-315. Data were derived from triplicate results. *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001, compared with control group.