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Diagram A and B shows the normal splicing patterns in which POLG1 E12 (A) and E19 (B) are predominantly included in human and the partially exon skipping that occurs in E12 and E19 are alternatively spliced. Panel C and D shows RT-PCR analysis of POLG1 E12 (C) and E19 (D) splicing patterns in patients' blood (n = 3).
