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. 2012 Dec 10;7(12):e51136. doi: 10.1371/journal.pone.0051136

Table 2. EMT-core list of 130 genes shared between at least 10 GES datasets.

Upregulated Downregulated
Cell adhesion and migration ADAM12, CDH11, CDH2, COL1A1, COL3A1, COL5A1, COL6A1, COL6A3, CTGF, CYP1B1, DLC1, FBLN1, FBLN5, FGF2, FGFR1, FN1, HAS2, LUM, MMP2, MYL9, NID2, NR2F1, NRP1, PLAT, PPAP2B, PRKCA, RECK, SERPINE1, SERPINE2, SPOCK1, TGM2, TNFAIP6, TPM1, VCAN, WNT5A CD24, CDH1, CXADR, CXCL16, DSG3, ELF3, EPCAM, EPHA, JUP, MPZL2, OVOL2, PLXNB1, S100P, SLC7A5, SYK
Development, cell differentiation and proliferation CDKN2C, EMP3, FBN1, IGFBP3, IL1R1, LTBP1, MME, PMP22, PTGER2, PTX3, SRGN, SULF1, SYNE1, TAGLN, TUBA1A, VIM, ZEB1 ABLIM1, ADRB2, ALDH1A3, ANK3, BIK CA2, CTSL2, FGFR2, FGFR3, FST, GJB3, IFI30, IL18, KLK7, KRT15, KRT17, LSR, MAP7, MBP, OCLN, PKP2, PPL, PRSS8, RAPGEF5, SPINT1
Angiogenesis and wound healing DCN, LOX, TFPI no gene with a major classification *
Metabolism ABCA1, GALNT10, SLC22A4 GPX3, SLC27A2, SMPDL3B, SORL1, ST6GALNAC2
Others or unclassified C5orf13, CDK14, EML1, FSTL1, LTBP2, MAP1B, RGS4, SYT11, TMEM158 AGR2, C10orf10, CDS1, FAM169A, FXYD3, KLK10, LAD1, MTUS1, PLS1, PRRG4, RHOD, SERPINB1, SLPI, TMEM30B, TPD52L1, TSPAN1, ZHX2, ZNF165

Categories have been chosen according to the GO classifications of the enrichment tools. Genes may be present in more than one category.

*

see Table S3 for more information.