Table 4.
Patients |
baseline creatinine |
24 month creatinine |
baseline proteinuria1 |
24 month proteinuria1 |
baseline cholesterol/ |
24 month cholesterol/ |
baseline triglycerides |
24 month triglycerides |
---|---|---|---|---|---|---|---|---|
|
(mg/dL)/MDRD (ml/min/1.73m2) |
(mg/dL)/ MDRD (ml/min/1.73m2) |
(mg/mmol) |
(mg/mmol) |
HDL/LDL |
HDL/LDL |
(mmol/L) |
(mmol/L) |
(mmol/L) | (mmol/L) | |||||||
1 |
0.84 /76 |
0.78/81 |
6.1 |
12.1 |
159/89/90 |
184/74/101 |
45 |
52 |
2 |
0.93/>90 |
0.95/>90 |
22.4 |
40.0 5 |
118/46/72 |
167/54/100 |
43 |
63 |
3 |
1.22/74 |
|
22.5 |
2 |
205/74/131 |
|
86 |
|
4 |
0.96/71 |
|
10.3 |
3 |
176/83/94 |
3 |
144 |
3 |
5 |
0.99/87 |
0.97/88 |
9.1 |
8.2 |
202/63/139 |
181/44/125 4 |
116 |
64 |
6 |
0.67/>90 |
0.58/>90 |
5.0 |
9.6 |
240/86/156 |
152/63/89 4 |
198 |
116 |
7 |
1.15/50 0 |
0.98/60 |
9.4 |
28.6 5 |
192/78/114 |
188/77/102 |
47 |
47 |
8 |
1.07/83 |
1.09/80 |
5.6 |
4.0 |
154/56/98 |
202/66/120 |
62 |
77 |
9 |
0.77/>90 |
0.86/>90 |
13.2 |
47.0 5 |
125/36/90 |
226/52/136 4 |
102 |
186 |
10 |
0.85/78 |
0.77/87 |
5.0 |
4.3 |
212/55/157 |
167/75/82 4 |
48 |
51 |
11 |
0.71/>90 0 |
0.86/78 |
7.7 |
9.4 |
94/40/54 |
118/41/64 |
76 |
62 |
12 |
0.42/> 90 |
0.48/>90 |
13.3 |
11.1 |
142/38/104 |
193/42/127 |
117 |
120 |
13 |
0.62/>90 |
0.61/>90 |
6.6 |
9.8 |
183/96/87 |
163/84/90 |
53 |
41 |
14 |
0.83/>90 |
1.01/>90 |
6.4 |
8.9 |
203/83/120 |
176/39/104 4 |
175 |
163 |
15 |
0.68/>90 |
0.69/>90 |
9.0 |
18.2 |
200/78/122 |
170/75/80 |
66 |
73 |
16 |
0.62/>90 |
0.54/>90 |
12.9 |
11.9 |
156/51/105 |
120/49/50 4 |
145 |
104 |
17 | 1.30/42 0 | 1.24/44 | 22.4 | 32.3 5 | 292/106/189 | 216/69/147 4 | 243 | 117 |
0-Patients 7, 11, 17 had undergone a nephrectomy at least one year before the start of the trial.
1-Expressed as a protein-to-creatinine ratio.
2-Patient 3 was withdrawn at 12 months of treatment due to nephrotic-range proteinuria that reverted after discontinuation of treatment.
3-Patient 4 was excluded at 10 months due to acute pyelonephritis and did not want to be rechallenged.
4-Statins were prescribed in patients 5, 6, 9, 10, 14, 16, 17.
5- ACEI were prescribed for microalbuminuria in patients 2, 7, 9, 17.