Figure 2. Ratios of investigated parameters and association to p27^Kip1expression.

(A) and (B): Representative staining for p27^Kip1, A: a prostate cancer sample with strong staining. B: a prostate cancer sample with weak staining. Bar = 100 µm. (C)–(F): Gene expression ratios are blotted against quantification of p27^Kip1 staining. Lines represents fit line ± Confidence Interval, N = 69. (C) Insulin receptor isoform A/Insulin receptor isoform B ratio. (D) IRS-1/IRS-2 ratio. (E) Insulin receptor isoform A/IGF 1 receptor ratio. (F) Insulin receptor isoform B/IGF 1 receptor ratio. Data were log_e-transformed prior to statistical analysis. Correlations were analyzed by linear regression analysis. IRS – Insulin receptor substrate; IGF – Insulin-like growth factor.