Table 3. Multivariate Cox proportional hazards analysis of overall survival of patients with uterine sarcoma, 1990–2008 (n = 1,137).
Variable | Group | People | Person-years | Deaths | HR | 95% CI | p |
Age(years) | |||||||
<30 | 48 | 305.2 | 10 | 0.84 | 0.44–1.60 | 0.60 | |
30–39 | 215 | 1317.8 | 47 | 0.90 | 0.64–1.27 | 0.54 | |
40–49 | 482 | 2718.4 | 111 | 1 | Referent | ||
50–59 | 265 | 1097.3 | 132 | 2.55 | 1.98–3.28 | <0.001 | |
60–69 | 86 | 334.8 | 51 | 3.53 | 2.52–4.93 | <0.001 | |
≥ 70 | 41 | 143.8 | 24 | 3.30 | 2.11–5.15 | <0.001 | |
Period | |||||||
1990–1994 | 135 | 1067.2 | 41 | 1.27 | 0.88–1.83 | 0.20 | |
1995–1999 | 255 | 1833.4 | 100 | 1 | Referent | ||
2000–2008 | 747 | 3016.6 | 234 | 1.52 | 1.08–2.14 | 0.015 | |
Subtype | |||||||
ESS | 278 | 1716.9 | 84 | 1 | referent | ||
LGESS | 135 | 624.2 | 5 | 0.13 | 0.05–0.32 | <0.001 | |
LMS | 670 | 3310.1 | 272 | 1.59 | 1.24–2.04 | <0.001 | |
Adenosarcoma | 54 | 266.0 | 14 | 0.83 | 0.47–1.46 | 0.52 |
HR: hazard ratio, CI: confidence interval, ESS: endometrial stromal sarcoma, LGESS: low grade endometrial stromal sarcoma, LMS: leiomyosarcoma.