Table 3. Calculated MRSI data of the PINK1 study cohort compared to age-matched healthy controls.

		controls(n = 23)	95%CI	PINK1 heterozygous(n = 9)	95%CI	PINK1 homozygous patient II.5	PINK1 homozygous patient II.7
rCho [mmol/l]	mesencephalon	0.39 (0.34)	0.24–0.55	0.31 (0.28)	0.03–0.60	0.008	0.001
	putamen	0.37 (0.28)	0.25–0.49	0.42 (0.29)	0.19–0.64	0.013	0.067
Cre [mmol/l]	mesencephalon	2.08 (0.89)	1.66–2.49	1.97 (0.75)	1.20–2.88	1.03	0.84
	putamen	3.52 (0.47)	3.32–3.72	3.76 (0.74)	3.19–4.33	2.09*	2.61
ADP [mmol/l]	mesencephalon	0.02 (0.01)	0.02–0.03	0.19 (0.01)	0.01–0.03	0.14	0.008
	putamen	0.05 (0.01)	0.05–0.06	0.06 (0.01)	0.05–0.07	0.03*	0.04

Data are given as mean (1SD). 95% CI = 95% confidence interval. Bold data with an asterisk mark values outside of the 2SD range of controls.