Table 4.
Correlations between pathological features and outcomes
| HR (95% CI) Univariate | P-value | HR (95% CI) Multivariateb | P-value | |
|---|---|---|---|---|
| Mesangial hypercellularity score (M) | ||||
| ≤0.5 |
1.0 |
0.1 |
1.0 |
0.6 |
| >0.5 |
2.1 (0.84-5.1) |
1.3 (0.49-3.4) |
||
| Endocapillary proliferation (E) | ||||
| Absent |
1.0 |
0.5 |
1.0 |
0.2 |
| Present |
0.67 (0.2-2.3) |
0.44 (0.12-1.5) |
||
| Segmental glomerulosclerosis or adhesion (S) | ||||
| Absent |
1.0 |
0.03 |
1.0 |
0.1 |
| Present |
9.2 (1.2-68.6) |
5.2 (0.6-43) |
||
| Tubular atrophy / interstitial fibrosis (T) | ||||
| T0 |
1.0 |
0.01 |
1.0 |
0.04 |
| T1 or T2 |
4.3 (1.8-10.5) |
2.9 (1.0-7.9) |
||
| Crescent (C) | ||||
| Absent |
1.0 |
0.2 | |
NS |
| Present | 1.8 (0.8-4.1) | |||
Abbreviations: CI, confidence interval; OR, odds ratio; HR, hazard ratio. NS, not significant.
bMultivariate Cox regression model: multivariate with four pathological features (M,E,S,T) + initial eGFR, MAP and proteinuria.