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. 2012 Dec 10;7(12):e51476. doi: 10.1371/journal.pone.0051476

Figure 5. Minimal effect of ionizing irradiation on tumor hypoxia.

Figure 5

Luciferase activity and tumor volume of A549 ODD-Luc-derived xenografts in control (B, D) and irradiated mice (A, C, 3×1 Gy) at a small (A, B, 200 mm3±10%) and at a large (C, D 400 mm3±10%) tumor volume at the day of treatment start (nIR = 5; ncontrol = 7). Fold induction of luciferase activity per tumor volume (solid line) and relative tumor volume (dotted line) were set to 1 at day 0. Error bars represent mean ±SE of fold induction luciferase activity/tumor volume or relative tumor volume per group.