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. 2012 Dec 11;7(12):e48286. doi: 10.1371/journal.pone.0048286

Table 2. Cortical thickness comparisons child sample.

Contrast Cortical region Hemisphere Talairach Size pmax
X Y Z (mm2)
All ADHD vs Control
Control>ADHD Inferior Parietal* L −47.4 −58.1 41.0 7817.34 1.16E-07
Superior Parietal*
Cuneus*
Inferior Parietal* R 36.1 −74.6 33.1 12932.79 4.80E-10
Superior Parietal*
Cuneus
Lateral Occipital
Middle Temporal
Lingual*
Fusiform
Lingual* L −6.3 −80.8 0.2 3190.14 1.98E-05
Fusiform
Precentral* L −39.0 −5.4 54.0 2126.83 1.27E-06
Superior Frontal*
Caudal Middle Frontal
Precentral* R 46.5 −5.2 44.4 2797.57 2.70E-06
Superior Frontal*
Orbitofrontal * L −35.1 38.1 −10.4 5547.78 2.79E-06
Rostral Middle Frontal*
Inferior Frontal
Orbitofrontal R 19.6 60.4 −3.3 2421.24 2.14E-05
Rostral Middle Frontal
Control<ADHD -
Medicated ADHD vs Control
Control>ADHD Inferior Parietal* L −47.4 −58.1 41.0 7577.90 2.12E-07
Superior Parietal*
Precuneus
Cuneus
Superior Frontal
Inferior Parietal* R 36.1 −74.6 33.1 12534.43 3.99E-10
Superior Parietal*
Superior Frontal*
Cuneus
Lateral Occipital
Inferior Temporal
Lingual*
Fusiform
Lingual* L −7.6 −81.6 −0.3 2654.72 7.33E-05
Fusiform
Precentral* L −38.4 −5.5 53.6 2767.74 2.17E-06
Postcentral
Orbitofrontal* L −35.3 37.5 −10.2 2677.03 5.96E-06
Rostral Middle Frontal
Superior Frontal
Inferior Frontal
Orbitofrontal R 9.1 29.9 −19.2 1451.53 1.91E-04
Rostral Middle Frontal
Control<ADHD -

Full results of the ‘control>ADHD’ comparison in the child groups including all ADHD subjects. The second section of the table provides the results of the same comparisons including only those patients with a history of pharmacological treatment with psychostimulant medication. Results are thresholded at p<0.05, MCTSB corrected for multiple comparisons. No clusters of thicker cortical mantle were observed in the ADHD sample compared to the control children (contrast ‘control<ADHD’).

*

Clusters in these regions also survive a threshold of p<0.001, MCTSB corrected for multiple comparisons.