Table 3. Cortical thickness comparisons adult sample.
| Contrast | Cortical region | Hemisphere | Talairach | Size | pmax | ||
| X | Y | Z | (mm2) | ||||
| All ADHD vs Control | |||||||
| Control>ADHD | Superior Parietal | R | 15.7 | −72.9 | 43.6 | 90.84 | 2.10E-04 |
| Superior Frontal | R | 10.8 | 6.1 | 38.3 | 3.85 | 7.19E-04 | |
| Posterior Cingulate | L | 5.42 | −1.2 | −16.1 | 5.42 | 2.68E-04 | |
| Postcentral | L | −35.3 | −24.1 | 46.3 | 8.72 | 3.12E-04 | |
| Control<ADHD | Temporal Pole | L | −43.7 | 12.4 | −31.0 | 102.30 | 4.18E-04 |
| Orbitofrontal | R | 29.1 | 20.8 | −21.3 | 39.22 | 4.96E-04 | |
| Pars Opercularis | R | 53.5 | 14.9 | 2.3 | 24.62 | 6.78E-04 | |
| Medicated ADHD vs Control | |||||||
| Control>ADHD | Superior Parietal | R | 15.6 | −72.6 | 42.5 | 220.93 | 3.03E-05 |
| Inferior Parietal | L | −45.3 | −69.4 | 18.6 | 14.66 | 5.81E-04 | |
| Precentral | L | −33.3 | −24.6 | 46.7 | 10.31 | 1.43E-04 | |
| Control<ADHD | Orbitofrontal | R | 46.5 | 27.9 | −9.3 | 167.56 | 2.04E-04 |
| Medicated ADHD vs Medication-Naïve ADHD | |||||||
| Med.Naïve>Med.ADHD | Inferior Parietal | L | −59.6 | −26.2 | 36.8 | 16.36 | 7.08E-04 |
| R | 41.1 | −57.1 | 18.4 | 85.09 | 3.56E-05 | ||
| Superior Frontal | R | 22.0 | 39.0 | 35.6 | 21.79 | 5.47E-04 | |
| Mid-Cingulate | L | −14.5 | −34.2 | 46.4 | 2.87 | 8.39E-04 | |
| Lingual | L | −21.6 | −81.1 | −6.0 | 24.92 | 6.70E-04 | |
| Fusiform | R | 26.8 | −68.5 | −4.3 | 25.90 | 4.01E-04 | |
| Lateral Occipital | R | 28.6 | −96.1 | 1.1 | 2.53 | 9.82E-04 | |
| Med.Naïve<Med.ADHD | - | ||||||
Full results of the ‘control>ADHD’ and ‘control<ADHD’ comparisons involving the complete adult ADHD sample (a combination of the medication-naïve (Med.Naïve ADHD) and medicated adult ADHD groups (Med.ADHD), as well as the comparisons including only the medicated patients with ADHD. The peak value of the posterior cingulate cortex cluster is actually located in the dorsal part of the corpus callosum directly adjacent to the posterior cingulate cortex, although the cluster extends primarily to the posterior cingulate cortex. The last section of the table represents the differences between the medication-naïve ADHD group and the medicated ADHD patients. Results are thresholded at p<0.001 uncorrected. No results were obtained for these comparisons at a threshold of p<0.05 MCTSB corrected for multiple comparisons.